After this initial success, other pharmaceutical companies began to introduce other benzodiazepine derivatives. It is two and a half times more potent than its predecessor, chlordiazepoxide, which it quickly surpassed in terms of sales.
12.1 Patients at a high risk for abuse, dependence, tolerance, or addictionĭiazepam was the second benzodiazepine to be invented by Sternbach of Hoffmann-La Roche, and was approved for use in 1963. Diazepam is used to treat a wide range of conditions and has been one of the most frequently prescribed medications in the world for the past 40 years. ĭiazepam is a core medicine in the World Health Organization's " Essential Drugs List", which is a list of minimum medical needs for a basic health care system. It may also be used before certain medical procedures (such as endoscopies) to reduce tension and anxiety, and in some surgical procedures to induce amnesia. It is commonly used for treating anxiety, insomnia, seizures, alcohol withdrawal, and muscle spasms. It possesses anxiolytic, anticonvulsant, sedative, skeletal muscle relaxant and amnestic properties. Prescription Only (S4) (AU) Schedule IV (CA) Schedule IV (US) Schedule IV (International)ĭiazepam ( IPA: /daɪˈæzɨpæm/), first marketed as Valium by Hoffmann-La Roche) is a benzodiazepine derivative drug.
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